- One of the key properties of HPMC is its ability to form gels in water. This makes it an excellent choice for thickening liquids, such as sauces, soups, and cosmetics. When HPMC is added to a liquid, it absorbs water and swells, creating a gel-like texture. The thickness and viscosity of the gel can be adjusted by varying the concentration of HPMC in the liquid.
hpmc is intended as an auxiliary during ophthalmologic interventions and examinations.
- On the other hand, low-viscosity HPMC is more suitable for applications that require a fluid or liquid consistency. For example, it is commonly used as a coating agent for tablets or as a suspending agent in suspensions. Low-viscosity HPMC also has a lower gelling temperature, making it ideal for use in cold environments Low-viscosity HPMC also has a lower gelling temperature, making it ideal for use in cold environments
Low-viscosity HPMC also has a lower gelling temperature, making it ideal for use in cold environments Low-viscosity HPMC also has a lower gelling temperature, making it ideal for use in cold environments
hpmc grades and uses.
- In the pharmaceutical industry, HPMC Ltd’s products are often used as a binder in tablet formulations
hpmc ltd. HPMC can improve the hardness, disintegration, and drug release of tablets, making it a valuable ingredient for pharmaceutical manufacturers. It is also used in ophthalmic preparations, topical creams, and suspensions due to its thickening and stabilizing properties. - higher DS and MW will result in a slower release rate and increased viscosity,
- The solubility of HPMC has significant implications in various industries. In pharmaceuticals, it serves as a binder, coating agent, and controlled-release matrix in tablets. In construction, it is used as a thickener, adhesive, and water retention agent in mortar and plasters. In the food industry, it acts as a stabilizer and emulsifier, while in cosmetics, it finds use as a film-forming agent.
- Furthermore, HPMC is a key component in the food industry, where it serves as a food additive, thickener, and emulsifier. It is commonly used in dairy products, baked goods, and sauces, contributing to their texture and stability.
- The price of redispersible polymer powder is primarily determined by the type and quality of the polymer used, production processes, and market supply and demand dynamics. Generally, these powders are derived from vinyl acetate-ethylene (VAE), polyvinyl acetate (PVA), or acrylic copolymers, with VAE being the most commonly used due to its excellent re-dispersion and adhesion properties. The cost of raw materials, especially petrochemicals, plays a crucial role in determining the final product price.
- Do not use 2 doses or extra doses.

Why do we use HPMC capsules?
There are data for microcrystalline cellulose (E 460), methyl cellulose (E 461), hydroxypropyl cellulose (E 463) and sodium carboxymethyl cellulose (E 466), which were tested in mice, rats, hamsters and/or rabbits with oral dosing or via gavage. As regards microcrystalline cellulose (E 460) studies have been conducted in rats (dietary exposure) with a mixture including guar gum or sodium carboxymethylcellulose (E 466) (15% in either case). The NOAEL for both maternal and developmental toxicity were the highest experimental dosages, i.e. 4,500 mg/kg bw (for mixture with guar gum) and 4,600 mg/kg bw (for mixture with sodium carboxymethyl cellulose). Methyl cellulose (E 461) was examined in mice, rats, hamsters and rabbits. In two different studies, pregnant mice were exposed via gavage (vehicle corn oil) to a dose range of 16-1,600 mg methyl cellulose (E 461)/kg bw per day from day 6 to 15 of gestation, followed by a caesarean section at day 17 of gestation. In the first study, maternal toxicity (increase in mortality and reduced pregnancy rate in the survivors) as well as retarded ossification in fetuses were noticed at the highest tested level, pointing to a NOAEL of 345 mg methyl cellulose (E 461) mg/kg bw per day (the last but one highest dosage) in mice. In the second study, no maternal toxicity and fetal abnormalities were observed in mice exposed up to 700 mg methyl cellulose (E 461) mg/kg bw per day. Rat studies (n = 2) were performed in pregnant dams exposed via gavage (vehicle corn oil) to a dose range of 16-1,320 mg methyl cellulose (E 461) mg/kg bw per day from day 6 to 15 of gestation followed by a caesarean section at day 20. In the first study (0, 13, 51, 285 or 1,320 mg methyl cellulose (E 461)/kg bw per day) the highest tested dosage resulted in no maternal toxicity but also in increased incidence of extra centres of ossification in vertebrae of fetuses from high dose dams; in a second rat study, the incidence of such alteration slightly increased in fetuses from the highest dosed group (1,200 mg methyl cellulose (E 461)/kg bw per day). Based on the above results, a NOAEL of 285 mg methyl cellulose (E 461) mg/kg bw per day could be identified in rats. No maternal or fetal toxicity was detected in Golden hamsters exposed via gavage (vehicle corn oil) up to 1,000 mg methyl cellulose (E 461) mg/kg bw per day from day 6 to 10 of gestation followed by a caesarean section at day 20. The study on rabbits was discarded due to poor experimental design. The only relevant developmental toxicity study with hydroxypropyl cellulose (E 463) (dissolved in 1% gum arabic solution) was performed in pregnant rats exposed via gavage from day 7 to 17 of gestation to 0, 200, 1,000 or 5,000 mg/kg bw test item and some of them subjected to caesarean sections at day 20. No treatment-related adverse effects were detected in dams or in the examined fetuses. A number of dams were allowed to deliver and no clinical, behavioural or morphological changes were observed in the examined pups. Their reproductive ability was seemingly not affected and no abnormalities were found in the F1-derived fetuses. The in utero exposure to the highest dose (5,000 mg/kg bw per day) may be considered as the NOAEL of methyl cellulose (E 461) for this study. No mortality, and no adverse effects were observed on implantation or on fetal survival in pregnant mice or rats dosed via gavage with up to 1,600 mg sodium carboxymethyl cellulose (E 466)/kg bw per day.
Answer: HPMC in the application of putty powder, thickening, water retention and construction of three roles. Thickening: Cellulose can be thickened to suspension, so that the solution to maintain uniform up and down the role of the same, anti-hanging. Water retention: Make putty powder dry slowly, assist ash calcium reaction under the action of water. Construction: cellulose has lubricating effect, can make putty powder has good construction property. HPMC does not participate in any chemical reactions, but only plays an auxiliary role. Putty powder and water, on the wall, is a chemical reaction, because of the formation of new substances, the putty powder on the wall off the wall, ground into powder and then use, will not work, because a new substance (calcium carbonate) has been formed. The main components of ash calcium powder are: Ca(OH)2, CaO and a small amount of CaCO3 mixture,
CaO+H2O=Ca(OH)2 - Ca(OH)2+CO2=CaCO3↓+H2O Ash calcium generates calcium carbonate under the action of CO2 in water and air, while HPMC only holds water to assist ash calcium to react better, and itself does not participate in any reaction.